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18 July 2019 - 18 July 2019

Flux-sensing by transporter/kinase pairs – need-based activation of antibiotic resistance.

Abstract:  Resistance against antimicrobial peptides in many Gram-positive bacteria is mediated by detoxification systems that are comprised of a two-component regulatory system and an ATP-binding-cassette (ABC) transporter. The histidine kinases of these systems depend entirely on the transporter for detection of antimicrobial peptides, suggesting...

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