[University of Bologna Press Release]

IFR is a partner in a new EU-funded research project that is investigating how diet can help ensure that we remain healthy during old age. Immunological studies will feed into a study of how diet can affect a number of age-related conditions.

People are living longer. Rising living standards, improved lifestyle and better education, as well as greater access to quality healthcare services has meant that we can expect to reach 78 years of age, an increase of six years compared to the 1980s. However, data also shows that Europeans live to just over 60 years without being limited in their day-to-day activities by ill-health or disabilities*. This is a challenge. What can we do to enable people to be healthier, for longer? And as a growing proportion of people in the European population are over 65 – predicted to reach 40% by 2030 – preventing age-related disease will also reduce associated medical and social costs.

This is the subject of a new European Commission-funded project called NU-AGE, that is looking at new dietary strategies addressing the specific needs of elderly population in Europe. Starting this month the project will explore how diet can help European seniors to live a healthier, longer life.

Diet and ageing
Many factors – both biological and environmental – play a role in ageing. Diet is one such factor and scientific opinion today is that by carefully selecting our diet we can affect the ageing process. But how does it work?

The influence of diet on age-related conditions is a relatively unexplored area of research and it is unclear as to what the optimal diet would be. What we do know, however, is that the food we eat can influence the development of inflammation. This is important because inflammation associated with ageing has been shown to be one factor in the development of age-related diseases such as atherosclerosis (thickening of artery walls and a risk factor for hearth disease), type 2 diabetes and neurodegeneration leading to cognitive decline.

NU-AGE research
The 5-year NU-AGE project will start by designing  a new food pyramid for those over 65 years old.  This will be developed from food based dietary guidelines used in Europe, illustrating the proportions of different foods that should be included in a balanced diet. The NU-AGE 65+ food pyramid will be designed to meet the nutritional needs of the elderly by emphasising nutrient-density, water, dietary fibre, vitamin D and vitamin B12. To study the effects of the NU-AGE food pyramid on health and ageing factors, elderly citizens across Europe will receive advice, fortified foods and other support to adjust their diets to match the pyramid. Food intake data, blood, urine and other samples will be collected and the results will be compared to those of elderly people not taking part in the dietary intervention. Alongside the dietary intervention, socio-economic determinants for food choice in the elderly will be investigated.

At the Institute of Food Research, scientists led by Professor Claudio Nicoletti and Professor Simon Carding will be conducting immunological studies that will contribute to the NU-AGE project. “We are going to monitor as to whether a specific type of diet has an impact on innate and adaptive immune response, by checking several parameters in elderly people pre and post dietary intervention,” said Prof. Nicoletti.

The study will cover 1250 people over the age of 65 from all over Europe, as well as 125 people recruited for detailed analysis in collaboration with the University of East Anglia, looking for immunological markers of ageing and the impact a Mediterranean based diet has on improving immunity in old age.

Based on the knowledge gained about influences of diet on ageing and its potential to prevent age-related disease, foods designed especially for elderly consumers will be developed and the best ways to communicate dietary recommendations to those over 65 will be explored.

Coordinator of the project, Professor Franceschi at the University of Bologna says: “Through its work, NU-AGE will seek to fill the current lack of knowledge on how the whole diet can impact on and counteract age-related disease and functional decline. This will contribute to improved health and quality of life in our ageing population in Europe.”.

The results will be valuable to a wide range of stakeholders – from the scientific community and health professionals to industry and policy makers – and contribute to the work of the European Commission’s recently launched Pilot European Innovation Partnership on Active and Healthy Ageing**.

References:
*OECD (2010), Health at a Glance: Europe 2010, OECD Publishing. Available at: http://dx.doi.org/10.1787/health_glance-2010-en
**Pilot European Innovation Partnership on Active and Healthy Ageing website: http://ec.europa.eu/research/innovation-union/index_en.cfm?section=active-healthy-ageing

Notes to editor:

NU-AGE is a multidisciplinary consortium consisting of 31 partners from 17 EU countries. Involved are research institutes across Europe, large food industries, traditional food companies, one biotech SME and associations of the European food and drink industry. Coordinator for the project is Prof. Claudio Franceschi at University of Bologna, Italy. Communications are managed by the European Food Information Council (EUFIC).

For more information about the project please contact Cecilia Wanhainen at cecilia.wanhainen@eufic.org or on +32 2 506 89 89.