Aleks Gontarczyk

Research Assistant

Contact via email

Mechanisms regulating the gut-liver axis during health and disease

I graduated from University of Sheffield with a BSc in Genetics and an MSc in Molecular Medicine.

Next, I took up a cell-engineering role at Horizon Discovery in Cambridge, where I used rAAV or CRISPR/Cas technology to introduce mutations into cell lines.

I returned to academia for a PhD in Dr Stephen Robinson’s lab. My project was on endothelial cell biology in the context of anti-angiogenic strategies. I carried on in the same group, as a post-doc, and I investigated the impact of gut microbiota on the vascular system development and function.

My current role is to provide support to the research into the gut-microbiome-liver axis in metabolic health

 

Key Publications

  • Atkinson SJ, Gontarczyk AM, Alghamdi AAA, Ellison TS, Johnson RT, Fowler WJ, Kirkup BM, Silva BC, Harry BE, Schneider JG, Weilbaecher KN, Mogensen MM, Bass MD, Parsons M, Edwards DR and Robinson SD. “The β3-integrin endothelial adhesome regulates microtubule dependent cell migration.” EMBO Reports. 2018. e44578. DOI: 10.15252/embr.201744578
  • Steri V, Ellison TS, Gontarczyk AM, Weilbaecher K, Schneider JG, Edwards DR, Fruttiger M, Hodivala-Dilke KM and Robinson SR. “Acute Depletion of Endothelial β3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice”. Circulation Research. 2014. 114:79-91. DOI: 10.1161/circresaha.114.301591