Aleks Gontarczyk

Researcher

Contact via email

Microbiota and vascular health

I graduated from the University of Sheffield with a BSc in Genetics and an MSc in Molecular Medicine. In 2013, I volunteered in Dr Stephen Robinson’s laboratory at the University of East Anglia and helped with projects related to integrins in angiogenesis.

I then moved on to a cell-engineering role at Horizon Discovery in Cambridge. My role was to use rAAV or CRISPR/Cas technology to generate cell lines ordered by clients.

I returned to the Robinson Lab in 2015 as a PhD student. My project aimed to characterize the integrin adhesions in endothelial cells in the context of improving anti-angiogenic therapies. In the beginning of 2019, I have made the transition to become a post-doc.

My current work aims to understand the impact of gut microbiota on the vascular system development and function

 

Key Publications

  • Atkinson SJ, Gontarczyk AM, Alghamdi AAA, Ellison TS, Johnson RT, Fowler WJ, Kirkup BM, Silva BC, Harry BE, Schneider JG, Weilbaecher KN, Mogensen MM, Bass MD, Parsons M, Edwards DR and Robinson SD. “The β3-integrin endothelial adhesome regulates microtubule dependent cell migration.” EMBO Reports. 2018. e44578. DOI: 10.15252/embr.201744578
  • Steri V, Ellison TS, Gontarczyk AM, Weilbaecher K, Schneider JG, Edwards DR, Fruttiger M, Hodivala-Dilke KM and Robinson SR. “Acute Depletion of Endothelial β3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice”. Circulation Research. 2014. 114:79-91. DOI: 10.1161/circresaha.114.301591