Andrew Bell

Postgraduate Student

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Glycobiology of host-microbe interactions in the gut

My PhD project focuses on the impact of bacterial sialic acid metabolism on gut homeostasis. In particular I am interested in how a novel bacterial mechanism of utilising mucin-derived sialic acid may provide a competitive advantage to bacteria expressing an intramolecular trans-sialidases, and help to protect the gut from pathogens.

I studied Biochemistry at the University of East Anglia, and as part of the degree programme undertook a year in Industry placement in Dr Claire Domoney’s lab at the John Innes Centre where I was involved in a project to increase understanding of chlorophyll degradation and turnover pathways in plants.

I returned to Dr Domoney’s lab after completing my undergraduate where I continued the same research theme and discovered that the SGRL protein can regulate chlorophyll metabolism contributing to plant growth and development in pea.

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