My project will look at how the early life microbiota modulates vaccine responses; I am examining how specific microbes may improve immune responses to vaccination. My Ph.D. is also in collaboration with Prof Simon Carding, as his group is interested in how molecules produced by microbes, such as membrane vesicles, influence immune cell populations including dendritic cells. Depending on the outcome, we might be able to improve vaccine responses in children by supplementing with novel live biotherapeutics and/or boost the immune response against certain vaccines without the need for additional adjuvants.