I graduated from Leeds University with a BSc in Microbiology. I then moved to Cardiff University and obtained a PhD in microbial metabolism of xenobiotic compounds. After a short postdoctoral position in the Biochemistry department of Cardiff University I joined the Institute of Food Research, Norwich in 1989 and have worked on a number of industrially funded biotechnology projects on the engineering of lactic acid bacteria and yeast for production of novel food ingredients and antimicrobials.

Currently I am the translational microbiome group leader at the Institute where my research is focused on understanding the role of gut bacteria in health and disease of humans and animals.

My group has developed probiotic bacteria for reducing the levels of foodborne pathogens such as Campylobacter from the food chain. I have worked on the relationship between gut microbiota and specific gastrointestinal disorders; IBS and Ulcerative Colitis. In collaboration with clinicians at the Norfolk and Norwich University Hospital my group is actively involved in setting up a bacteriotherapy service for the treatment of Clostridium difficile infections, and are exploring how the exploitation of new technologies could be used to improve the diagnosis of gastrointestinal infections.

I have published more than 100 research papers and have filed 9 international patents. I have been appointed a Visiting Professor at Jiangnan University in China and have recently established a BBSRC funded UK-China joint centre for research on probiotics.

Key Publications

Pettersson S., Korecka A., Dona D., Lahiri S., Tett A., Al-Asmakh M., Braniste V., D’Arienzo R., Abbaspour A., Reichardt N., Fujii-Kuriyama Y., Rafter R., Narbad A., Holmes E., Nicholson J., Arulampalam V. (2016) Bidirectional communication between the gut microbiome and the Aryl-Hydrocarbon-Receptor (AhR) influences host energy homeostasis as well as microbiome composition in the small intestine, NPJ Biofilms and Microbiomes. 16014;

Dunne M., Mertens H. D. T., Garefalaki V., Jeffries C. M., Thompson A., Svergun D., Mayer M. J., Narbad A., Meijers R. (2014) The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor. PLOS Pathogens. 10: e1004228

Dertli E., Colquhoun I.J., Gunning A.P., Bongaerts R. J., Le Gall, G., Bonev B., Mayer M. J., Narbad A. (2013) Structure and biosynthesis of two exopolysaccharides produced by Lactobacillus johnsonii  FI9785. Journal of Biological Chemistry.  288:31938-51

Horn N., Wegmann U., Dertli E., Mulholland F., Collins S. R. A., Waldron K. W., Bongaerts R. J., Mayer M. J., Narbad A. (2013) Spontaneous mutation reveals influence of exopolysaccharide on Lactobacillus johnsonii surface characteristics PLOS ONE

Manes-Lazaro R., van Diemen P. M., Pin C., Mayer M. J., Stevens M. P., Narbad A.(2017) Administration of Lactobacillus johnsonii FI9785 to chickens affects colonisation by Campylobacter jejuni and the intestinal microbiota, British Poultry Science. In press

Garcia Gutierrez E., O'Connor P. M., Saalbach G., Walsh C. J., Hegarty J. W., Guinane C. M., Mayer M. J., Narbad A., Cotter P. D.. (2020)

First evidence of production of the lantibiotic nisin P

Scientific Reports

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Garcia-Gutierrez E., O'Connor P., Colquhoun I. J., Vior N. M., Rodriguez J. M., Mayer M. J., Cotter P. D., Narbad A.. (2020)

Production of multiple bacteriocins, including the novel bacteriocin gassericin M, by Lactobacillus gasseri LM19, a strain isolated from human milk

Applied Microbiology and Biotechnology

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Garcia Gutierrez E., Walsh C. J., Sayavedra L., Diaz-Calvo T., Thapa D., Ruas-Madiedo P., Mayer M. J., Cotter P. D., Narbad A.. (2020)

Genotypic and phenotypic characterization of fecal Staphylococcus epidermidis isolates suggests plasticity to adapt to different human body sites

Frontiers in Microbiology

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Diaz M., Sayavedra L., Atter A., Mayer M. J., Amoa-Awua W., Narbad A., Saha S.. (2020)

Lactobacillus garii sp. nov., isolated from a fermented cassava product.

International journal of systematic and evolutionary microbiology

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Parmanand B., Kellingray L., Le Gall G., Basit A., Fairweather S., Narbad A.. (2019)

A decrease in iron availability to human gut microbiome reduces the growth ofpotentially pathogenic gut bacteria; an in vitro colonic fermentation study

Journal of Nutritional Biochemistry, 67, 20-27

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Tran T. T. T., Corsini S., Kellingray L., Hegarty C., Le Gall G., Narbad A., Müller M., Tejera N., O'Toole P. W., Minihane A. M., Vauzour D.. (2019)

APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology.

FASEB Journal, fj201900071R

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Bisharat L., Barker S. A., Narbad A., Craig D. Q. M.. (2019)

In vitro drug release from acetylated high amylose starch-zein films for oral colon-specific drug delivery.

International Journal of Pharmaceutics, 556, 311-319

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