Bacterial niche adaptation
My research interests are rooted in microbial systems and the challenge of antimicrobial resistance.
I did my undergraduate studies at The University of Edinburgh in Biomedical Sciences with specialisation in Infectious Diseases and a research project at the Roslin Institute. My project was about creating an infection model to explore virulence plasmids in Rhodococcus equi and the dependency on plasmids for infection.
I followed up with an MSc in Microbiology and Infection at the University of Birmingham. My project involved elucidating a novel molecular chaperone involved in protein secretion under the Sec pathway in E. coli. I utilised Transposon-Directed Insertion Sequencing (TraDIS) to identify synthetic lethal knockouts of non-essential Sec components to identify the chaperone’s role in protein secretion.
In 2020, I started a PhD in Gemma Langridge’s group exploring how different antimicrobial mode of actions affect ATP production in E. coli. My work contributes towards diagnosing urinary tract infections in humans and informing treatment.