Ebenezer Foster-Nyarko

Postgraduate Student

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Bacterial Genomics and Metagenomics

I am a PhD student in Professor Mark Pallen’s group in the Quadram Institute. My PhD research is focused on “Foodborne infection and the Microbial Ecology of the Vertebrate Gut”. This work is building on previous data on the gut microbiomes of chickens and guinea-fowl from the Gambia which I generated in Prof. Pallen’s lab in Warwick Medical School in 2016, published work from my supervisors’ labs, including access to novel sequencing platforms in Norwich (Oxford Nanopore in the O’Grady lab).

I began my academic career in the University of Ghana where I read BSc in Biomedical Laboratory Sciences, majoring in Clinical Microbiology for my final year thesis. I also trained in Staffordshire University, UK for my MSc in Molecular Biology, and have over the past five years been involved in Invasive Bacterial Disease surveillance in Professor Martin Antonio’s lab in the Medical Research Council Unit The Gambia (MRCG).

In 2016 I was the lead Clinical Microbiologist in a team of experts from MRCG who provided technical assistance to the Ministry of Health in Ghana during the pneumococcal meningitis outbreak. I characterized for the first time during the outbreak, the strain of pneumococcus that was responsible for the outbreak (S. pneumoniae serotype 1).

My previous research experience has included utilising clinical microbiological and molecular techniques to investigate the efficacy of novel as well as existing vaccines, antibiotic resistance and understanding the colonization of respiratory pathogens. My publications and co-authored works are available here https://www.ncbi.nlm.nih.gov/pubmed/?term=Foster-Nyarko+E.

Key Publications

First Author publications1. Incidence of Macrolide-Lincosamide-Streptogramin B Resistance amongst Beta-haemolytic Streptococci in The Gambia.(PMID: 28231812)2.

Associations between carriage of Group B Streptococcus(GBS) and other respiratory pathogens during early infancy.(PMID: 27230066)

Co-Authored Publications1.Efficiency of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: a phase 2, randomized, controlled, observer-blind study.(PMID: 28389097)

Isolation of methicillin resistant Staphylococcus aureus (MRSA) and multi-drug resistant Elizabethkingia meningoseptica from neonates within minutes of birth. (PMID: 27941472)

An outbreak of pneumococcal meningitis among older children(>5years) and adults after the implementation of an infant vaccination programme with the 13-valent pneumococcal conjugate vaccine in Ghana. (PMID: 27756235)

Foster-Nyarko E,Alikhan NF,Ikumapayi UN,Sarwar G,Okoi C,Tientcheu PM,Defernez M,O J,Antonio M,Pallen MJ. (2021)

Genomic diversity of Escherichia coli from healthy children in rural Gambia.


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Foster-Nyarko E,Alikhan NF,Ravi A,Thilliez G,Thomson N,Baker D,Kay G,Antonio M,O J,Pallen MJ. (2020)

Genomic diversity of Escherichia coli isolates from non-human primates in the Gambia

Microbial Genomics, 6

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Ravi A., Halstead F. D., Bamford A., Casey A., Thomson N. M., van Schaik W., Snelson C., Goulden R., Foster-Nyarko E., Savva G. M., Whitehouse T., Pallen M., Oppenheim B. A.. (2019)

Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients.

Microbial genomics, Volume 5, Issue 9, 10.1099/mgen.0.000293

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