I obtained a BSc in Microbiology and an MSc in Molecular Medicine from the University of Sheffield. I then pursued PhD project at the University of Liverpool in collaboration with The Medicines and Healthcare products Regulatory Agency (MHRA), investigating the role of the gut microbiome in the development of colitis as an immune-related adverse event to checkpoint inhibitor therapy, using a multi-omics approach. In addition to my PhD research, I contributed to the development of gut microbiome standards at the MHRA.

In 2025, I joined the Quadram Institute to work with Professor Arjan Narbad and Dr Ngozi Elumogo, in collaboration with Norfolk and Norwich University Hospital. This collaboration focuses on investigating the role of the human gut microbiome in gastrointestinal disorders and the gut-brain axis, including the use of bacteriotherapy for the treatment of Parkinson’s Disease. Additionally, I will explore the dynamics of changes in the structure of the gut microbiome following Faecal Microbiota Transplantation (FMT), with the goal of expanding the application of this technology.

My current research interests are centred on the standardisation of microbiome research, the interactions between the gut microbiome and the immune system, and multivariate modelling.

Key publications

Jacob Dehinsilu, Chrysi Sergaki, Vanessa Fontana, Munir Pirmohamed

The interplay between the microbiome and colonic immune system in checkpoint inhibitor therapy Front. Microbiomes, 03 March 2023 Sec. Host and Microbe Associations Volume 2 – 2023 doi.org/10.3389/frmbi.2023.1061193