Dr James Lazenby

Senior Researcher

Contact via email

Bacterial lifestyles



I recently moved to Norwich to continue working with Professor Cynthia Whitchurch on investigating bacterial lifestyles so as to discover innovative treatment strategies.

In 2011 I was awarded my PhD from the University of New South Wales, Australia. My PhD research was on investigating the interaction of bacterially produced signaling molecules and how they interact with the host. From there, I went to work with Professor Miguel Camara at the University of Nottingham, U. K., where I was part of an E. U. funded project that identified novel virulence targets in the major opportunistic human pathogen, Pseudomonas aeruginosa and continued with my work with an MRC funded project led by Professor Paul Williams, at the University of Nottingham, where I also investigated novel ways of reducing animals in research by utilizing live animal imaging with fluorescent and luminescent tagged bacterial strains. In 2015 I went to work with Professor Cynthia Whitchurch at the ithree institute within the University of Technology Sydney, Australia. In this project I investigated the role of explosive cell lysis on the in vivo virulence of P. aeruginosa.

My scientific interests are still on investigating bacteria and host interactions and utilizing the most cutting-edge imaging techniques to better elucidate this interaction in situ. I am also an advocate for the three R’s in animal research: Replace, Refine, Reduce and research ways that those principles can be introduced without compromising scientific quality.

Hynen AL,Lazenby JJ,Savva GM,McCaughey LC,Turnbull L,Nolan LM,Whitchurch C. (2021)

Multiple holins contribute to extracellular DNA release in Pseudomonas aeruginosa biofilms.

Microbiology (Reading, England)

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Hamidian M,Lazenby J,To J,Hartstein R,Soares J,McNamara S,Whitchurch C. (2020)

Complete Genome Sequence of Stenotrophomonas maltophilia Strain CF13, Recovered from Sputum from an Australian Cystic Fibrosis Patient.

Microbiology resource announcements, 9, e00628-20

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