Dr Lee Kellingray
I obtained a first class degree in Microbiology at the University of East Anglia in 2011, and joined the Quadram Institute Science in the same year to do a PhD looking at the effects of Brassica vegetables on the human gut microbiota. Following my PhD I joined the Translational Microbiome group as a research scientist to work with Professor Arjan Narbad to examine how pathogenic bacteria interact with the human gut microbiota, and investigate the potential of next generation sequencing as a clinical diagnostic tool.
I am currently involved in a successful collaboration with the Norfolk and Norwich University Hospital providing bacteriotherapy to patients with recurrent Clostridium difficile infection. In addition to this I am using in vitro colon models and 1H NMR to examine the effects of gut pathogens, such as Salmonella typhimurium, on the gut microbiota through metagenomic and metabolomic analyses.
My current interests are focused on the role of the gut microbiota in health, specifically host-microbe and microbe-microbe interactions, and how this research can be translated to improved health outcomes for the general public.
Systemic iron reduction by venesection alters the gut microbiome in patients with haemochromatosis.
JHEP reports : innovation in hepatology
A decrease in iron availability to human gut microbiome reduces the growth ofpotentially pathogenic gut bacteria; an in vitro colonic fermentation study
Journal of Nutritional Biochemistry, 67, 20-27