Dr Lee Kellingray


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Translational microbiome


I obtained a first class degree in Microbiology at the University of East Anglia in 2011, and joined the Quadram Institute Science in the same year to do a PhD looking at the effects of Brassica vegetables on the human gut microbiota. Following my PhD I joined the Translational Microbiome group as a research scientist to work with Professor Arjan Narbad to examine how pathogenic bacteria interact with the human gut microbiota, and investigate the potential of next generation sequencing as a clinical diagnostic tool.

I am currently involved in a successful collaboration with the Norfolk and Norwich University Hospital providing bacteriotherapy to patients with recurrent Clostridium difficile infection. In addition to this I am using in vitro colon models and 1H NMR to examine the effects of gut pathogens, such as Salmonella typhimurium, on the gut microbiota through metagenomic and metabolomic analyses.

My current interests are focused on the role of the gut microbiota in health, specifically host-microbe and microbe-microbe interactions, and how this research can be translated to improved health outcomes for the general public.

Goldenberg S. D., Batra R., Beales I., Digby-Bell J. L., Irving P. M., Kellingray L., Narbad A., Franslem-Elumogo N.. (2018)

Comparison of Different Strategies for Providing Fecal Microbiota Transplantation to Treat Patients with Recurrent Clostridium difficile Infection in Two English Hospitals: A Review

Infectious Diseases and Therapy

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Kellingray L., Le Gall G., Defernez M., Beales I. L., Franslem-Elumogo N., Narbad A.. (2018)

Microbial taxonomic and metabolic alterations during faecal microbiota transplantation to treat Clostridium difficile infection

Journal of Infection

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Ying S., Kellingray L., Zhai Q., Le Gall G., Narbad A., Zhao J., Zhang H., Chen W.. (2018)

Structural and functional alterations in the microbial community and immunological consequences in a mouse model of antibiotic-induced dysbiosis

Frontiers Microbiology

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Shi Y., Kellingray L., Le Gall G., Zhao J., Zhang H., Narbad A., Zhai Q., Chen W.. (2018)

The divergent restoration effects of Lactobacillus strains in antibiotic-induced dysbiosis

Journal of Functional Foods, 51, 142-152

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Le Gall G., Guttula K., Kellingray L., Tett A. J., ten Hoopen R., Kemsley K. E., Savva G. M., Ibrahim A., Narbad A.. (2018)

Metabolite quantification of faecal extracts from colorectal cancer patients and healthy controls


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Kellingray L., Tapp H. S., Saha S., Doleman J. F., Narbad A., Mithen R. F.. (2017)

Consumption of a diet rich in Brassica vegetables is associated with a reduced abundance of sulphate-reducing bacteria: a randomised crossover study

Molecular Nutrition & Food Research

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