Dr Lizbeth Sayavedra

Researcher

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Translational microbiome

Links/websites:

I did my MSc and PhD at the Max Planck Institute for Marine Microbiology in Bremen, Germany. My PhD focused on host-symbiont interaction and metabolism of sulfur-oxidising and methane-oxidising symbionts from deep-sea mussels.

At the Quadram Institute I am working on sulfate-reducing bacteria that reside in the GI tract of humans and animals and the role they play in the development of inflammatory conditions. Specifically, I am developing molecular genetic tools to identify how the bacterium Desulphovibrio piger colonises and maintains the association with other members of the gut microbiome.


Key Publications

Rubin-Blum M, Antony CP, Borowski C, Sayavedra L, Pape T, Sahling H, Bohrmann G, Dubilier N. Short-chain alkanes fuel the metabolism of symbiotic Cycloclasticus from deep-sea gas and petroleum seeps. Nature Microbiology. doi: 10.1038/nmicrobiol.2017.93

Ponnudurai RP, Kleiner M, Sayavedra L, Petersen J, Moche M, Otto A, et al. (2016). Metabolic and physiological interdependencies in the Bathymodiolus azoricus symbiosis. ISME. doi:10.1038/ismej.2016.124

Breusing C, Biastoc A, Drews A, Metaxas A, Jollivet D, Vrijenhoek RC, Bayer T, Melzner F, Sayavedra L., et al. (2016). Biophysical and population genetic models predict the presence of “phantom” stepping stones connecting Mid-Atlantic Ridge vent ecosystems. Current Biology. doi: 10.1016/j.cub.2016.06.062

Sayavedra L, Kleiner M, Ponnudurai R, Wetzel S, Pelletier E, Barbe V, et al. (2015). Abundant toxin-related genes in the genomes of beneficial symbionts from deep-sea hydrothermal vent mussels. eLife 4. doi: 10.7554/eLife.07966

Rubin-Blum M., Antony C. P., Sayavedra Camacho L., Martínez-Pérez C., Birgel D., Peckmann J., Wu Y. C., Cardenas P., MacDonald I., Marcon Y., Sahling H., Hentschel U., Dubilier N.. (2019)

Fueled by methane: deep-sea sponges from asphalt seeps gain their nutrition from methane-oxidizing symbionts.

The ISME journal


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Ansorge R., Romano S., Sayavedra L., Porras M. Á. G., Kupczok A., Tegetmeyer H. E., Dubilier N., Petersen J.. (2019)

Functional diversity enables multiple symbiont strains to coexist in deep-sea mussels.

Nature microbiology


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Ponnudurai R., Heiden S. E., Sayavedra L., Hinzke T., Kleiner M., Hentschker C., Felbeck H., Sievert S. M., Schlüter R., Becher D., Schweder T., Markert S.. (2019)

Comparative proteomics of related symbiotic mussel species reveals high variability of host-symbiont interactions.

The ISME journal


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Diaz M., Wegmann U., Akinyemi N., Oguntoyinbo F., Sayavedra L., Mayer M. J., Narbad A.. (2018)

Complete Genome Sequence of Ochrobactrum haematophilum FI11154, Isolated from Kunu-Zaki, a Nigerian Millet-Based Fermented Food.

Genome announcements, 6


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Diaz M., Wegmann U., Akinyemi N., Oguntoyinbo F. A., Sayavedra L., Mayer M., Narbad A.. (2018)

Complete Genome Sequence of Ochrobactrum haematophilum FI11154, Isolated from Kunu-Zaki, a Nigerian Millet-Based Fermented Food.

Genome announcements, 6


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