Martina Poletti

Postgraduate Student

Contact via email

Systems Biology of Gut-Microbe Interactions

I am a BBSRC DTP PhD student within the Korcsmáros group based at Earlham Institute, where in collaboration with Lindsay Hall at Quadram Institute, I am focusing on understanding how Bifidobacteria modulate autophagy in the gut.

In my PhD project, I aim to combine computational and experimental approaches, including state-of-the-art organoid-based screening, to identify specific pathways through which Bifidobacteria modulate autophagy, and by doing this, influence intestinal homeostasis. Studying these microbe-host connections is essential to understand the mechanisms behind beneficial effects of commensal bacteria.

I hold a BSc in Biotechnology from the University of Pavia (Italy) and an MSc in Molecular Nutrition and Toxicology from Wageningen University (Netherlands). My passion for microbiology started when investigating S. aureus bacterial biofilms during a semester abroad at Aarhus University, Denmark. During my MSc thesis at Wageningen University, I used transcriptomics data and bioinformatics to study the effect of dark chocolate intake on cardiovascular disease.

I am passionate about making science accessible to all. I have myself worked as a scientific communicator for the European Food Information Council based in Brussels, where I collaborated on European projects focused on nutrition, health and sustainability.

Hautefort I, Poletti M, Papp D, Korcsmaros . (2022)

Everything You Always Wanted to Know About Organoid-Based Models (and Never Dared to Ask)

Cellular and Molecular Gastroenterology and Hepatology

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Poletti M, Treveil A, Csabai L, Gul L, Modos D, Madgwick M, Olbei M, Bohar B, Valdeolivas A, Turei D, Verstockt B, Triana S, Alexandrov T, Saez-Rodriguez J, Stanifer ML, Boulant S, Korcsmaros . (2022)

Mapping the epithelial-immune cell interactome upon infection in the gut and the upper airways.

NPJ systems biology and applications

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Olbei M,Hautefort I,Modos D,Treveil A,Poletti M,Gul L,Shannon-Lowe C,Korcsmaros T. (2021)

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

Frontiers in Immunology

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Treveil A,Bohar B,Sudhakar P,Gul L,Csabai L,Olbei M,Poletti M,Madgwick M,Andrighetti T,Hautefort I,Modos D,Korcsmaros T. (2021)

ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways

PLoS Computational Biology

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Poletti M,Arnauts K,Ferrante M,Korcsmaros T. (2020)

Organoid-based models to study the role of host-microbiota interactions in IBD

Journal of Crohns and Colitis

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