I am interested in all aeras of microbiology, with a particular focus on identifying novel drug targets and exploring antimicrobial natural products to combat harmful human and food borne pathogens.

My research journey began during my PhD study at Glycomics and Glycan Bioengineering Center (GGBRC), Nanjing Agricultural university, where I characterized various types of carbohydrate-active enzymes and applied them to structure analysis of complex glycans and synthesis of functional oligosaccharides.

Following my PhD, I worked in University of Cambridge as a research associate, characterising key enzymes involved in fatty acid metabolism in Pseudomonas aeruginosa using various biochemical and microbiological and structural biology approaches.

Currently at Quadram Institute, I am using the TraDIS-Xpress technique to investigate P. aeruginosa biofilms under ciprofloxacin treatment, with the goal to discover potential antibiofilm targets.

Key Publications

Wang, M., Medarametla, P., Kronenberger, T. et al. Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity. Nat Commun 16, 2334 (2025).

Wang, M., Zhang, X.-Y., Guo, R.-R. et al. (2018). Cloning, purification and biochemical characterization of two β-N-acetylhexosaminidases from the mucin-degrading gut bacterium Akkermansia muciniphila. Carbohydrate Research, 457, 1-7.