Dr Raymond Kiu

Researcher

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Early life microbiota-host interactions

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I obtained a BSc in Nutritional and Health Sciences from Taipei Medical University under which programme I was professionally trained as a clinical dietitian. I then completed an MSc with distinction at the University of Reading in Nutritional Sciences (2013) before I went on to study for a PhD (2015-2018) in Microbiology at the University of East Anglia (UEA) under the supervision of Dr Lindsay Hall, and was partly funded by UEA Faculty of Medicine and Health Sciences International Bursary.

My PhD focused on understanding the role of Clostridium perfringens in intestinal diseases using genomics (Whole Genome Sequencing), characterising phenotypic virulence traits and establishing a disease model to understand C. perfringens intestinal infections.


Key Publications

Kiu R & Hall LJ. An update on the human and animal enteric pathogen Clostridium perfringens. Emerging Microbes & Infections 7, 141. 2018. DOI:10.1038/s41426-018-0144-8

Kiu R, Caim S, Alexander S, Pachori P, Hall LJ. Probing genomic aspects of the multi-host pathogen Clostridium perfringens reveals significant pangenome diversity, and a diverse array of virulence factors. Front Microbiol 8, 2485. 2017. DOI:10.3389/fmicb.2017.02485

Kiu R, Caim S, Alcon-Giner C, Belteki G, Clarke P, Pickard D, Dougan G, Hall LJ. Preterm infant-associated Clostridium tertium, Clostridium cadaveris, and Clostridium paraputrificum strains: genomic and evolutionary insights. Genome Biology and Evolution 9,10. 2017. DOI:10.1093/gbe/evx210

Lopez-Tello J, Kiu R, Schofield Z, Dalby MJ, van Sinderen, Gall GL, Hall LJ, Sferruzzi-Perri AN. (2025)

Placental endocrine function is controlled by maternal gut Bifidobacterium in germ-free mice.

Journal of translational medicine


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Phillips S, Kiu R, Darby EM, Alcon-Giner C, Acuna-Gonzalez A, Camargo A, Lamberte L, Sim K, Shaw AG, Clarke P, Schaik W, Kroll S, Hall LJ. (2025)

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants. 

Nature Communications


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Kujawska M, Seki D, Chalklen L, Malsom J, Kiu R, Goatcher S, Christoforou I, Mitra S, Crouch L, Hall LJ. (2025)

Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts.

Cell host & microbe


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Kiu R, Darby EM, Alcon-Giner C, Acuna-Gonzalez A, Camargo A, Lamberte LE, Phillips S, Sim K, Shaw AG, Clarke P, van Schaik, Kroll JS, Hall LJ. (2025)

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants.

Nature communications


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Jain V, Dalby MJ, Alexander EC, Burford C, Acford-Palmer H, Serghiou IR, Teng NMY, Kiu R, Gerasimidis K, Zafeiropoulou K, Logan M, Verma A, Davenport M, Hall LJ, Dhawan A. (2024)

Association of gut microbiota and gut metabolites and adverse outcomes in biliary atresia: A longitudinal prospective study.

Hepatology communications


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Dalby MJ, Kiu R, Serghiou IR, Miyazaki A, Acford-Palmer H, Tung R, Caim S, Phillips S, Kujawska M, Matsui M, Iwamoto A, Taking B, Cox SE, Hall LJ. (2024)

Faecal microbiota and cytokine profiles of rural Cambodian infants linked to diet and diarrhoeal episodes.

NPJ biofilms and microbiomes


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Lopez-Tello J, Kiu R, Schofield Z, Zhang CXW, van Sinderen, Le Gall, Hall LJ, Sferruzzi-Perri AN. (2024)

Maternal gut Bifidobacterium breve modifies fetal brain metabolism in germ-free mice.

Molecular metabolism


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Camargo A, Ramírez JD, Kiu R, Hall LJ, Muñoz M. (2024)

Unveiling the pathogenic mechanisms of Clostridium perfringens toxins and virulence factors.

Emerging microbes & infections


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Related Case Studies

Bifidobacterium breve, a key memeber of the maternal microbiome

Targeting a life-threatening gut condition in preterm babies

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