Dr Raymond Kiu

Researcher

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Early life microbiota-host interactions

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I obtained a BSc in Nutritional and Health Sciences from Taipei Medical University under which programme I was professionally trained as a clinical dietitian. I then completed an MSc with distinction at the University of Reading in Nutritional Sciences (2013) before I went on to study for a PhD (2015-2018) in Microbiology at the University of East Anglia (UEA) under the supervision of Dr Lindsay Hall, and was partly funded by UEA Faculty of Medicine and Health Sciences International Bursary.

My PhD focused on understanding the role of Clostridium perfringens in intestinal diseases using genomics (Whole Genome Sequencing), characterising phenotypic virulence traits and establishing a disease model to understand C. perfringens intestinal infections.


Key Publications

Kiu R & Hall LJ. An update on the human and animal enteric pathogen Clostridium perfringens. Emerging Microbes & Infections 7, 141. 2018. DOI:10.1038/s41426-018-0144-8

Kiu R, Caim S, Alexander S, Pachori P, Hall LJ. Probing genomic aspects of the multi-host pathogen Clostridium perfringens reveals significant pangenome diversity, and a diverse array of virulence factors. Front Microbiol 8, 2485. 2017. DOI:10.3389/fmicb.2017.02485

Kiu R, Caim S, Alcon-Giner C, Belteki G, Clarke P, Pickard D, Dougan G, Hall LJ. Preterm infant-associated Clostridium tertium, Clostridium cadaveris, and Clostridium paraputrificum strains: genomic and evolutionary insights. Genome Biology and Evolution 9,10. 2017. DOI:10.1093/gbe/evx210

Seki D, Pollak S, Kujawska M, Kiu R, Acuna-Gonzalez A, Crouch LI, Bakshani CR, Chivers PT, Mommers M, van Best, Penders J, Hall LJ. (2026)

Human milk oligosaccharide mediates mutualism between Escherichia coli and Bifidobacterium bifidum.

Nature communications


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Chapman JA, Masi AC, Beck LC, Watson H, Young GR, Browne HP, Shao Y, Kiu R, Nelson A, Doyle JA, Palmowski P, Lengyel M, Connolly JPR, Lamb CA, Porter A, Lawley TD, Hall LJ, Embleton ND, Perry JD, Berrington JE, Stewart CJ. (2026)

Clostridia from preterm infants metabolize human milk oligosaccharides to suppress pathobionts and modulate intestinal function in organoids.

Nature microbiology


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Lopez-Tello J, Kiu R, Schofield Z, Dalby MJ, van Sinderen, Gall GL, Hall LJ, Sferruzzi-Perri AN. (2025)

Placental endocrine function is controlled by maternal gut Bifidobacterium in germ-free mice.

Journal of translational medicine


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Phillips S, Kiu R, Darby EM, Alcon-Giner C, Acuna-Gonzalez A, Camargo A, Lamberte L, Sim K, Shaw AG, Clarke P, Schaik W, Kroll S, Hall LJ. (2025)

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants. 

Nature Communications


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Kujawska M, Seki D, Chalklen L, Malsom J, Kiu R, Goatcher S, Christoforou I, Mitra S, Crouch L, Hall LJ. (2025)

Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts.

Cell host & microbe


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Kiu R, Darby EM, Alcon-Giner C, Acuna-Gonzalez A, Camargo A, Lamberte LE, Phillips S, Sim K, Shaw AG, Clarke P, van Schaik, Kroll JS, Hall LJ. (2025)

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants.

Nature communications


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Jain V, Dalby MJ, Alexander EC, Burford C, Acford-Palmer H, Serghiou IR, Teng NMY, Kiu R, Gerasimidis K, Zafeiropoulou K, Logan M, Verma A, Davenport M, Hall LJ, Dhawan A. (2024)

Association of gut microbiota and gut metabolites and adverse outcomes in biliary atresia: A longitudinal prospective study.

Hepatology communications


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Dalby MJ, Kiu R, Serghiou IR, Miyazaki A, Acford-Palmer H, Tung R, Caim S, Phillips S, Kujawska M, Matsui M, Iwamoto A, Taking B, Cox SE, Hall LJ. (2024)

Faecal microbiota and cytokine profiles of rural Cambodian infants linked to diet and diarrhoeal episodes.

NPJ biofilms and microbiomes


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Related Case Studies

Bifidobacterium breve, a key memeber of the maternal microbiome

Targeting a life-threatening gut condition in preterm babies

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