Dr Rebecca Ansorge

Postdoctoral Researcher

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Microbial Genomes, Strains and Evolution

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I am a postdoctoral researcher in the Hildebrand Lab at the Quadram Institute and a member of the “Gut Microbes and Health” Institute Strategic Programme (GMH). I have a strong interest in metagenomics and other cultivation-independent techniques to study the microbiome in order to extend and complement cultivation-based approaches.  Currently, I am investigating strain-level variation and microbial pangenome diversity in human gut microbiomes.
I did my PhD at the Max Planck Institute for Marine Microbiology in Bremen, Germany, focusing on microdiversity of microbial symbionts in animal-microbe symbioses by using metagenomics and bioinformatic approaches.
I am fascinated my host-microbe interactions and how this links to strain-diversity – from highly specific one-to-one symbioses to complex microbiomes such as those in the human gut.

Key Publications

Ansorge R,Birolo G,James SA,Telatin A (2021) Dadaist2: a toolkit to automate and simplify statistical analysis and plotting of metabarcoding experiments. International Journal of Molecular Sciences, http://dx.doi.org/10.3390/ijms22105309

Uecker M,Ansorge R,Sato Y,Sayavedra L,Breusing C,Dubilier N (2021)Deep-sea mussels from a hybrid zone on the Mid-Atlantic Ridge host genetically indistinguishable symbionts. The ISME Journal http://dx.doi.org/10.1038/s41396-021-00927-9

Ansorge R,Romano S,Sayavedra L,Rubin-Blum M,Gruber-Vodicka H,Scilipoti S,Molari M,Dubilier N,Petersen JM (2020) The hidden pangenome: comparative genomics reveals pervasive diversity in symbiotic and free-living sulfur-oxidizing bacteria. bioRxiv (preprint) https://www.biorxiv.org/content/10.1101/2020.12.11.421487v1

Hinger I, Ansorge R, Mussmann M, Romano S (2020) Phylogenomic analyses of members of the widespread marine heterotrophic genus Pseudovibrio suggest distinct evolutionary trajectories and a novel genus, Polycladidibacter gen. nov. Applied and Environmental Microbiology, https://doi.org/10.1128/AEM.02395-19

Ansorge R, Romano S, Sayavedra L, Gonzáles Porras MÁ, Kupczok A, Tegetmeyer HE, Dubilier N, Petersen J (2019) Functional diversity enables multiple symbiont strains to coexist in deep-sea mussels. Nature Microbiology, https://doi.org/10.1038/s41564-019-0572-9

James S,Phillips S,Telatin A,Baker D,Ansorge R,Clarke P,Hall LJ,Carding S. (2020)

Preterm Infants Harbour a Rapidly Changing Mycobiota That Includes Candida Pathobionts

Journal of Fungi, 6, 273


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