Dr Rebecca Ansorge

Postdoctoral Researcher

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Microbial Genomes, Strains and Evolution

View Falk Hildebrand's group

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Biography

Recent Publications

I am a postdoctoral researcher in the Hildebrand Lab at the Quadram Institute and a member of the “Gut Microbes and Health” Institute Strategic Programme (GMH). I have a strong interest in metagenomics and other cultivation-independent techniques to study the microbiome in order to extend and complement cultivation-based approaches. Currently, I am investigating strain-level variation and microbial pangenome diversity in human gut microbiomes.

I did my PhD at the Max Planck Institute for Marine Microbiology in Bremen, Germany, focusing on microdiversity of microbial symbionts in animal-microbe symbioses by using metagenomics and bioinformatic approaches.

I am fascinated my host-microbe interactions and how this links to strain-diversity – from highly specific one-to-one symbioses to complex microbiomes such as those in the human gut.

Key Publications

Ansorge R,Birolo G,James SA,Telatin A (2021) Dadaist2: a toolkit to automate and simplify statistical analysis and plotting of metabarcoding experiments. International Journal of Molecular Sciences, http://dx.doi.org/10.3390/ijms22105309

Uecker M,Ansorge R,Sato Y,Sayavedra L,Breusing C,Dubilier N (2021)Deep-sea mussels from a hybrid zone on the Mid-Atlantic Ridge host genetically indistinguishable symbionts. The ISME Journal http://dx.doi.org/10.1038/s41396-021-00927-9

Ansorge R,Romano S,Sayavedra L,Rubin-Blum M,Gruber-Vodicka H,Scilipoti S,Molari M,Dubilier N,Petersen JM (2020) The hidden pangenome: comparative genomics reveals pervasive diversity in symbiotic and free-living sulfur-oxidizing bacteria. bioRxiv (preprint) https://www.biorxiv.org/content/10.1101/2020.12.11.421487v1

Hinger I, Ansorge R, Mussmann M, Romano S (2020) Phylogenomic analyses of members of the widespread marine heterotrophic genus Pseudovibrio suggest distinct evolutionary trajectories and a novel genus, Polycladidibacter gen. nov. Applied and Environmental Microbiology, https://doi.org/10.1128/AEM.02395-19

Ansorge R, Romano S, Sayavedra L, Gonzáles Porras MÁ, Kupczok A, Tegetmeyer HE, Dubilier N, Petersen J (2019) Functional diversity enables multiple symbiont strains to coexist in deep-sea mussels. Nature Microbiology, https://doi.org/10.1038/s41564-019-0572-9

Parker A, Romano S, Ansorge R, Aboelnoer A, Le Gall G, Savva G, Telatin A, Jones E, Baker D, Rudder S, Blackshaw LA, Jeffery G, Carding S. (2022)

Heterochronic fecal microbiota transfer reverses hallmarks of the aging gut, brain, and eye.

Microbiome

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Uecker M,Ansorge R,Sato Y,Sayavedra L,Breusing C,Dubilier N. (2021)

Deep-sea mussels from a hybrid zone on the Mid-Atlantic Ridge host genetically indistinguishable symbionts

The ISME Journal

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Ansorge R,Birolo G,James SA,Telatin A. (2021)

Dadaist2: a toolkit to automate and simplify statistical analysis and plotting of metabarcoding experiments

International Journal of Molecular Sciences

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Hsieh SY, Tariq M, Telatin A, Ansorge R, Adriaenssens E, Savva G, Booth C, Wileman T, Hoyles L, Carding S. (2021)

Comparison of PCR versus PCR-free DNA library preparation for characterising the human faecal virome

Viruses

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Mckee A, Kirkup B, Madgwick M, Fowler W, Price C, Dreger S, Ansorge R, Makin K, Caim S, Le Gall G, Pavely J, Leclaire C, Dalby M, Alcon-Giner C, Andrusaite A, Feng TY, Di Modica M, Triulzi T, Tagliabue E, Milling S, Weilbaecher K, Rutkowski M, Korcsmaros T, Hall L, Robinson S. (2021)

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth

iScience

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James S,Phillips S,Telatin A,Baker D,Ansorge R,Clarke P,Hall LJ,Carding S. (2020)

Preterm Infants Harbour a Rapidly Changing Mycobiota That Includes Candida Pathobionts

Journal of Fungi, 6, 273

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