Ryan Griffiths

Postgraduate Student

Glycobiology of host-microbe interactions in the gut

View Nathalie Juge's group

Biography

I am currently on the 4-year DTP PhD program at the Quadram Institute Biosciences titled “Structure and Function of the Accessory Secretion System” in the Juge Group (2018-2022). The accessory secretion system is a dedicated transport mechanism for large cell surface glycoprotein adhesins and is expressed by several gram-positive gut symbionts, which feeds into my interests elucidating the underlying mechanism of the gut microbiome and host relationship.

Previously, I completed an integrated Masters at the University of East Anglia in Microbiology (2014-2018) and took part in the Max Planck Junior Scholars Program at the Max Planck Institute for Brain Research (Frankfurt am Main) in 2013-2014.

Baker DJ,Aydin A,Le Viet T,Kay GL,Rudder S,de Oliveira Martins L,Tedim AP,Kolyva A,Diaz M,Alikhan NF,Meadows L,Bell A,Gutierrez AV,Trotter AJ,Thomson NM,Gilroy R,Griffith L,Adriaenssens EM,Stanley R,Charles IG,Elumogo N,Wain J,Prakash R,Meader E,Mather AE,Webber M,Dervisevic S,Page AJ,O J. (2021)

CoronaHiT: high-throughput sequencing of SARS-CoV-2 genomes.

Genome medicine

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Gold Lock

Wu H, Crost EH, Owen CD, van Bakel W, Martínez Gascueña A, Latousakis D, Hicks T, Walpole S, Urbanowicz PA, Ndeh D, Monaco S, Sánchez Salom L, Griffiths R, Reynolds RS, Colvile A, Spencer DIR, Walsh M, Angulo J, Juge N. (2021)

The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract.

PLoS biology

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Gold Lock

Page AJ, Mather AE, Le Viet T, Meader EJ, Alikhan NF, Kay GL, de Oliveira Martins L, Aydin A, Baker DJ, Trotter AJ, Rudder S, Tedim AP, Kolyva A, Stanley R, Yasir M, Diaz M, Potter W, Stuart C, Meadows L, Bell A, Gutierrez AV, Thomson NM, Adriaenssens EM, Swingler T, Gilroy RAJ, Griffith L, Sethi DK, Aggarwal D, Brown CS, Davidson RK, Kingsley RA, Bedford L, Coupland LJ, Charles IG, Elumogo N, Wain J, Prakash R, Webber MA, Smith SJL, Chand M, Dervisevic S, O'Grady J. (2021)

Large-scale sequencing of SARS-CoV-2 genomes from one region allows detailed epidemiology and enables local outbreak management.

Microbial genomics

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Gold Lock

Gaimster H., Hews C. L., Griffiths R., Soriano-Laguna M. J., Alston M., Richardson D. J., Gates A. J., Rowley G.. (2019)

A Central Small RNA Regulatory Circuit Controlling Bacterial Denitrification and N2O Emissions.

mBio, 10

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Gold Lock

Gaimster H., Hews C. L., Griffiths R., Soriano-Laguna M. J., Alston M., Richardson D. J., Gates A. J., Rowley G.. (2019)

A Central Small RNA Regulatory Circuit Controlling Bacterial Denitrification and N2O Emissions.

mBio, 10