Dr Sally Dreger

Senior Researcher

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Microbiota and vascular health

My work currently focuses on angiogenesis, in particular the interaction  between endothelial integrins and neuropilins in coordinating angiogenic responses. I am also interested in how the gut microbiome affects these interactions.

My previous postdoctoral position concentrated on investigating the role myoepithelial cells play in the angiogenic switch in ductal carcinoma in situ of the breast, during which I was short listed for the Royal Society of Medicine Sylvia Lawler Prize in Oncology.

My doctoral research examined the proliferation index and remodeling potential of human valve interstitial cells in biological scaffolds for which I received the Young Investigator Award from the International Society for Applied Cardiovascular Biology (ISACB). My postdoctoral research activities centered on investigating mesenchymal stem cell adhesion, viability and remodeling capacity to extracellular matrix proteins under both static and dynamic conditions.

I have worked in both government and private sector research facilities focusing on environmental microbiology, food microbiology & toxicology and animal virology.

Kiu R, Shaw AG, Sim K, Acuna-Gonzalez A, Price CA, Bedwell H, Dreger SA, Fowler WJ, Cornwell E, Pickard D, Belteki G, Malsom J, Phillips S, Young GR, Schofield Z, Alcon-Giner C, Berrington JE, Stewart CJ, Dougan G, Clarke P, Douce G, Robinson SD, Kroll JS, Hall L. (2023)

Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains.

Nature microbiology

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Dawoud MM, Jones DT, Chelala C, Abdou AG, Dreger SA, Asaad N, El-Wahed MA, Jone J. (2022)

Expression Profile of Myoepithelial Cells in DCIS: Do They Change From Protective Angels to Wicked Witches?

Applied Immunohistochemistry & Molecular Morphology, Vol. 30, No. 6, July 2022., 397-409

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Feng TY, Azar FN, Dreger SA, Buchta Rosean C, McGinty MT, Putelo AM, Kolli SH, Carey MA, Greenfield S, Fowler WJ, Robinson SD, Rutkowski M. (2022)

Reciprocal Interactions Between the Gut Microbiome and Mammary Tissue Mast Cells Promote Metastatic Dissemination of HR+ Breast Tumors

Cancer Immunol Res, 10(11), 13091325

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Feng T, Azar F, Buchta Rosen C, McGinty M, Putelo A, Koli S, Marino N, German R, Podicheti R, Dreger S, Fowler W, Greenfield S, Robinson S, Rutkowski . (2022)

Reciprocal interactions between the gut microbiome and mammary tissue mast cells promote metastatic dissemination of HR+ breast tumors

Cancer Immunology Research

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Mckee A, Kirkup B, Madgwick M, Fowler W, Price C, Dreger S, Ansorge R, Makin K, Caim S, Le Gall G, Pavely J, Leclaire C, Dalby M, Alcon-Giner C, Andrusaite A, Feng TY, Di Modica M, Triulzi T, Tagliabue E, Milling S, Weilbaecher K, Rutkowski M, Korcsmaros T, Hall L, Robinson S. (2021)

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth


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Wong PP,Muñoz-Félix JM,Hijazi M,Kim H,Robinson SD,De Luxán-Delg,Rodríguez-Hernández I,Maiques O,Meng YM,Meng Q,Bodrug N,Dukinfield MS,Reynolds LE,Elia G,Clear A,Harwood C,Wang Y,Campbell JJ,Singh R,Zhang P,Schall TJ,Matchett KP,Henderson NC,Szlosarek PW,Dreger SA,Smith S,Jones JL,Gribben JG,Cutillas PR,Meie P,Sanz-Moreno V,Hodivala-Dilke KM. (2020)

Cancer Burden Is Controlled by Mural Cell-ß3-Integrin Regulated Crosstalk with Tumor Cells

Cell, 181, 1346-1363.e21

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Moore M., Gammon L., Dreger S., Koh J., Garbe J. C., Stampfer M. R., Philpott M., Jones L., Bishop C. L.. (2018)

Ribosomal stress-induced senescence as a novel pro-senescence strategy for p16 positive basal-like breast cancer

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