Dr Shikha Saha

Researcher

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Optimising nutrient release from plant-based foods

I have extensive knowledge of analytical chemistry, especially chromatography (reversed phase, normal phase, chiral phase, mixed mode, and ion-exchange), spectroscopy (UV, fluorescence, IR, and NMR), and liquid chromatography–mass spectrometry (LC-MS and LC-MS/MS) techniques.

My work as a senior analytical scientist at the Food & Health Programme involves sample preparation, identification of unknown compounds in different matrices, protein-specific peptide identification, and quantitative analysis of wide range of phytochemicals in plant or biological fluids of human and animal origins.

I am responsible for the development of novel analytical methods for the analysis of plant, food, microbial and human metabolites.

I am responsible for training and supervising post-graduate students, visiting scientists and post-docs that are using HPLC, LC-MS and LC-MS/MS techniques as part of their research projects.

I liaise extensively with external contractors regarding all aspects of equipment maintenance, and with obtaining information regarding procurement of new instrumentation.

Davidson R, Watts L, Beasy G, Saha S, Kroon P, Cassidy A, Clark A, Fraser W, Mcnamara I, Kingsbury S, Conaghan P, Clark I, MacGregor . (2023)

AB1194 A proof of principle dietary intervention trial to examine the protective effect of broccoli bioactives, (specifically sulforaphane), on osteoarthritis

Annals of the Rheumatic Diseases


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Neequaye M, Steuernagel B, Saha S, Trick M, Troncoso-Rey P, van den, Traka MH, Østergaard L, Mithen . (2022)

Characterisation of the Introgression of Brassica villosa Genome Into Broccoli to Enhance Methionine-Derived Glucosinolates and Associated Health Benefits.

Frontiers in plant science


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Quesada-Vázquez S, Bone C, Saha S, Triguero I, Colom-Pellicer M, Aragonès G, Hildebrand F, Del Bas, Caimari A, Beraza N, Escoté . (2022)

Microbiota Dysbiosis and Gut Barrier Dysfunction Associated with Non-Alcoholic Fatty Liver Disease Are Modulated by a Specific Metabolic Cofactors’ Combination.

International journal of molecular sciences


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Speciale PJ, Bashllari R, Muscara C, Molonia MS, Saija A, Saha S, Wilde PJ, Cimino . (2022)

Anti-inflammatory activity of an in vitro digested anthocyanin-rich extract on intestinal epithelial cells exposed to TNF-a

Molecules, 27, 2022 Aug 23;27(17):5368


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Livingstone TL, Saha S, Bernuzzi F, Savva GM, Troncoso-Rey P, Traka MH, Mills RD, Ball RY, Mithen R. (2022)

Accumulation of Sulforaphane and Alliin in Human Prostate Tissue

Nutrients


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Bajka BH, Pinto AM, Perez-Moral N, Saha S, Ryden P, Ahn-Jarvi J, van der, Bland C, Berry SE, Ellis PR, Edwards C. (2022)

Enhanced secretion of satiety-promoting gut hormones in healthy humans following consumption of white bread enriched with cellular chickpea flour: A randomized cross-over study

The American Journal of Clinical Nutrition


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