Dr Sree Gowrinadh Javvadi


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Synthetic biology and biosynthetic pathways

I was introduced to this fascinating field of microbiology by Dr. Subhadeep Chatterjee and later nurtured by Dr. Vittorio Venturi, where I have obtained my PhD under his supervision (ICGEB, Italy). My research interests include Host-microbe interactions, Microbe-Microbe interactions and Microbial metabolisms.

As a Postdoctoral scientist in Dr. Hall’s group I had the opportunity to explore  Bifidobacterium metabolites involved in host immune-modulations and gut microbiome interactions through metabolomics and immunological approaches.

Currently as a research scientist in Prof Martin warren group I was involved in the development of detection methods for vitamin B12 from different biological samples and understand the kinetics between microbial proteins that bind to Vitamin B12.

Key Publications

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem Melissa A. E. Lawson, Ian J. O’Neill, Magdalena Kujawska, Sree Gowrinadh Javvadi, Anisha Wijeyesekera, Zak Flegg, Lisa Chalklen & Lindsay J. Hall. https://doi.org/10.1038/s41396-019-0553-2

Javvadi S, Pandey SS, Mishra A, Pradhan BB, Chatterjee S. Bacterial cyclic β-(1,2)-glucans sequester iron to protect against iron-induced toxicity. EMBO Rep. 2017;19(1):172-186. https://doi.org/10.15252/embr.201744650

Javvadi SG, Cescutti P, Rizzo R, et al. The spent culture supernatant of Pseudomonas syringae contains azelaic acid. BMC Microbiol. 2018;18(1):199. Published 2018 Nov 28. doi:10.1186/s12866-018-1352

Rai, R., Javvadi, S. and Chatterjee, S. (2015), Role of DSF in Xanthomonas iron uptake. Molecular Microbiology, 96: 708-727. doi:10.1111/mmi.12965.

Hitendra Kumar Patel, Patrizia Ferrante, Meng Xianfa, Sree Gowrinadh Javvadi, Sujatha Subramoni, Marco Scortichini, and Vittorio Venturi. Identification of Loci of Pseudomonas syringae pv. actinidiae Involved in Lipolytic Activity and Their Role in Colonization of Kiwifruit Leaves. Phytopathology 2017 107:6, 645-653. https://doi.org/10.1094/PHYTO-10-16-0360-R

Lawson M. A. E., O'Neill I. J., Kujawska M., Javvadi S., Wijeyesekera A., Flegg Z., Chalklen L., Hall L. J.. (2019)

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem.

The ISME journal

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