Dose-dependant acute or subacute disease caused by Burkholderia pseudomallei strain NCTC 13392 in a BALB/c aerosol model of infection.

Funnell S,Tree JA,Hatch GJ,Bate SR,Hall G,Pearson G,Rayner EL,Roberts ADG,Vipond J. (2019)

Journal of applied microbiology


The goal of this study was to examine, for the first time, the virulence and pathogenicity of aerosolized Burkholderia pseudomallei, strain NCTC 13392, in BALB/c mice in order to develop an animal model for testing novel medical countermeasures (MCMs) for the treatment of human acute and subacute (a disease state between acute and chronic) melioidosis.


Journal of applied microbiology


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