Identification of the anti-mycobacterial functional properties of piperidinol derivatives.

Guy C. S., Tichauer E., Kay G. L., Phillips D. J., Bailey T. L., Harrison J., Furze C. M., Millard A. D., Gibson M. I., Pallen M., Fullam E.. (2017)

British Journal of Pharmacology, 174, 2183-2193

Tuberculosis (TB) remains a major global health threat and is now the leading cause of death from a single infectious agent worldwide. The current TB drug regimen is inadequate, and new anti-tubercular agents are urgently required to be able to successfully combat the increasing prevalence of drug-resistant TB. The purpose of this study was to investigate a piperidinol compound derivative that is highly active against the Mycobacterium tuberculosis bacillus.

British Journal of Pharmacology, 174, 2183-2193

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