Incorporating prior knowledge improves detection of differences in bacterial growth rate.

Rickett L. M., Pullen N., Hartley M., Zipfel C., Kamoun S., Baranyi J., Morris R. J.. (2015)

BMC Systems Biology, 9, 60

Robust statistical detection of differences in the bacterial growth rate can be challenging, particularly when dealing with small differences or noisy data. The Bayesian approach provides a consistent framework for inferring model parameters and comparing hypotheses. The method captures the full uncertainty of parameter values, whilst making effective use of prior knowledge about a given system to improve estimation.

BMC Systems Biology, 9, 60

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