Phylogeny, resistome and mobile genetic elements of emergent OXA-48 and OXA-245 Klebsiella pneumoniae clones circulating in Spain.

Pérez-Vázquez M., Oteo J., García-Cobos S., Aracil B., Harris S. R., Ortega A., Fontanals D., Hernández J. M., Solís S., Campos J., Dougan G., Kingsley R. A.. (2016)

Journal of Antimicrobial Chemotherapy, 71, 887-96

The global emergence of OXA-48-producing Klebsiella pneumoniae clones is a significant threat to public health. We used WGS and phylogenetic analysis of Spanish isolates to investigate the population structure of blaOXA-48-like-expressing K. pneumoniae ST11 and ST405 and to determine the distribution of resistance genes and plasmids encoding blaOXA-48-like carbapenemases.

Journal of Antimicrobial Chemotherapy, 71, 887-96

View Publication