SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer.

Zubiete-Franco I., García-Rodríguez J. L., Lopitz-Otsoa F., Serrano-Macia M., Simon J., Fernández-Tussy P., Barbier-Torres L., Fernández-Ramos D., Gutiérrez-de-Juan V., López de Davalillo S., Carlevaris O., Beguiristain Gómez A., Villa E., Calvisi D., Martín C., Berra E., Aspichueta P., Beraza N., Varela-Rey M., Ávila M., Rodríguez M. S., Mato J. M., Díaz-Moreno I., Díaz-Quintana A., Delgado T. C., Martínez-Chantar M. L.. (2019)

EBioMedicine, 40, 406-421

Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular Carcinoma (HCC).

EBioMedicine, 40, 406-421

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