Systems Biology of Gut-Microbe Interactions

Tamas Korcsmaros

Dr Tamas Korcsmaros

Group Leader

Group: Korcsmaros group

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We aim to reconstruct intestinal cell, microbial strain, disease and patient specific signalling and regulatory networks, and integrate them in a multiscale system containing both host cells and microbes to understand molecular (patho)mechanisms.

Our key interests are the role of autophagy in intestinal inflammation and cancer, the systems biology of ulcerative colitis (a type of inflammatory bowel disease), and microbial rewiring of host regulatory processes.

The group combines in silico network biology methods with experimental validation and ‘omics approaches to explore and understand how pathogen and commensal microbes are affecting host processes.

We collaborate with many individuals and organisations throughout the world, including:

 

Korcsmaros group
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Our Targets

Targeting food safety

Food Safety

Targeting IBD

Inflammatory Bowel Disease (IBD)

Targeting the understanding of the microbiome

Understanding the Microbiome

Targeting cancer

Cancer

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